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Immunogenicity of a novel engineered HIV-1 clade C synthetic consensus-based envelope DNA vaccine
DNA vaccines require significant engineering in order to generate strong CTL responses in both non-human primates and humans. In this study, we designed a clade C env gene (EY3E1-C) to decrease the genetic distances of virus isolates within clade C and focus the induced T cell responses to conserved...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012758/ https://ncbi.nlm.nih.gov/pubmed/21651948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.05.076 |
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