Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice

There is no licensed vaccine or cure for human cytomegalovirus (CMV), a ubiquitous β-herpesvirus infecting 60–95% of adults worldwide. Infection can cause congenital abnormalities, result in severe disease in immunocompromised patients, and is a major impediment during successful organ transplantati...

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Detalhes bibliográficos
Main Authors: Shedlock, Devon J., Talbott, Kendra T., Wu, Stephan J., Wilson, Christine M., Muthumani, Karuppiah, Boyer, Jean D., Sardesai, Niranjan Y., Awasthi, Sita, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601142/
https://ncbi.nlm.nih.gov/pubmed/23151448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22447
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