A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer

por Nederlof, Iris, Horlings, Hugo M., Curtis, Christina, Kok, Marleen
Publicado en Cancers (Basel) (2021)

Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

por Persson, Marta, Andrén, Ywonne, Mark, Joachim, Horlings, Hugo M., Persson, Fredrik, Stenman, Göran
Publicado 2009

Low grade serous carcinoma of the peritoneum in a BRCA1 carrier previously diagnosed with a “low-grade serous tubal intra-epithelial carcinoma” (STIC) on risk reducing surgery

por Chay, Wen Yee, Horlings, Hugo M., Tinker, Anna V., Gelmon, Karen A., Gilks, C.Blake
Publicado en Gynecol Oncol Rep (2015)

Integration of Clinical and Gene Expression Data Has a Synergetic Effect on Predicting Breast Cancer Outcome

por van Vliet, Martin H., Horlings, Hugo M., van de Vijver, Marc J., Reinders, Marcel J. T., Wessels, Lodewyk F. A.
Publicado 2012

Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability

por van Vliet, Martin H, Reyal, Fabien, Horlings, Hugo M, van de Vijver, Marc J, Reinders, Marcel JT, Wessels, Lodewyk FA
Publicado 2008

Retrospective analysis of metastatic behaviour of breast cancer subtypes

por Savci-Heijink, C. Dilara, Halfwerk, Hans, Hooijer, Gerrit K. J., Horlings, Hugo M., Wesseling, Jelle, van de Vijver, Marc J.
Publicado en Breast Cancer Res Treat (2015)

Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer

por Lin, Cong, Majoor, Christof J., Roelofs, Joris J. T. H., de Kruif, Martijn D., Horlings, Hugo M., Borensztajn, Keren, Spek, C. Arnold
Publicado en BMC Cancer (2017)

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

por van de Vijver Marc J, Børresen-Dale Anne-Lise, Langerød Anita, Velds Arno, Horlings Hugo M, Holstege Henne, Nederlof Petra M, Jonkers Jos
Publicado 2010-11-01

SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets

por Nederlof Petra M, van Beers Eric H, van de Vijver Marc J, Horlings Hugo M, Lai Carmen, Wessels Lodewyk FA, Reinders Marcel JT
Publicado 2007-10-01

SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets

por Lai, Carmen, Horlings, Hugo M, van de Vijver, Marc J, van Beers, Eric H, Nederlof, Petra M, Wessels, Lodewyk FA, Reinders, Marcel JT
Publicado 2007

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

por Holstege, Henne, Horlings, Hugo M, Velds, Arno, Langerød, Anita, Børresen-Dale, Anne-Lise, van de Vijver, Marc J, Nederlof, Petra M, Jonkers, Jos
Publicado 2010

Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets

por Farazi, Thalia A, ten Hoeve, Jelle J, Brown, Miguel, Mihailovic, Aleksandra, Horlings, Hugo M, van de Vijver, Marc J, Tuschl, Thomas, Wessels, Lodewyk FA
Publicado 2014

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

por Pietersen, Alexandra M, Horlings, Hugo M, Hauptmann, Michael, Langerød, Anita, Ajouaou, Abderrahim, Cornelissen-Steijger, Paulien, Wessels, Lodewijk F, Jonkers, Jos, Vijver, Marc J van de, van Lohuizen, Maarten
Publicado 2008

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

por Léveillé, Nicolas, Elkon, Ran, Davalos, Veronica, Manoharan, Vijayalaxmi, Hollingworth, Dave, Vrielink, Joachim Oude, le Sage, Carlos, Melo, Carlos A., Horlings, Hugo M., Wesseling, Jelle, Ule, Jernej, Esteller, Manel, Ramos, Andres, Agami, Reuven
Publicado 2011

Abrogation of BRAF(V600E)-induced senescence by PI3K pathway activation contributes to melanomagenesis

por Vredeveld, Liesbeth C.W., Possik, Patricia A., Smit, Marjon A., Meissl, Katrin, Michaloglou, Chrysiis, Horlings, Hugo M., Ajouaou, Abderrahim, Kortman, Pim C., Dankort, David, McMahon, Martin, Mooi, Wolter J., Peeper, Daniel S.
Publicado 2012

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

por Groenendijk, Floris H, Mellema, Wouter W, van der Burg, Eline, Schut, Eva, Hauptmann, Michael, Horlings, Hugo M, Willems, Stefan M, van den Heuvel, Michel M, Jonkers, Jos, Smit, Egbert F, Bernards, René
Publicado en Int J Cancer (2015)

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition

por Bortnik, Svetlana, Choutka, Courtney, Horlings, Hugo M., Leung, Samuel, Baker, Jennifer H., Lebovitz, Chandra, Dragowska, Wieslawa H., Go, Nancy E., Bally, Marcel B., Minchinton, Andrew I., Gelmon, Karen A., Gorski, Sharon M.
Publicado en Oncotarget (2016)

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

por Turner, Nicholas, Lambros, Maryou B, Horlings, Hugo M., Pearson, Alex, Sharpe, Rachel, Natrajan, Rachael, Geyer, Felipe C, van Kouwenhove, Marieke, Kreike, Bas, Mackay, Alan, Ashworth, Alan, van de Vijver, Marc J, Reis-Filho, Jorge S
Publicado 2010

Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors

por Haltia, Ulla-Maija, Pihlajoki, Marjut, Andersson, Noora, Mäkinen, Lotta, Tapper, Johanna, Cervera, Alejandra, Horlings, Hugo M, Turpeinen, Ursula, Anttonen, Mikko, Bützow, Ralf, Unkila-Kallio, Leila, Carpén, Olli, Wilson, David B, Heikinheimo, Markku, Färkkilä, Anniina
Publicado en J Endocr Soc (2020)

Systematic analysis of somatic mutations impacting gene expression in 12 tumour types

por Ding, Jiarui, McConechy, Melissa K., Horlings, Hugo M., Ha, Gavin, Chun Chan, Fong, Funnell, Tyler, Mullaly, Sarah C., Reimand, Jüri, Bashashati, Ali, Bader, Gary D., Huntsman, David, Aparicio, Samuel, Condon, Anne, Shah, Sohrab P.
Publicado en Nat Commun (2015)