BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

BACKGROUND: Basal-like breast cancers (BLBC) are aggressive breast cancers for which, so far, no targeted therapy is available because they typically lack expression of hormone receptors and HER2. Phenotypic features of BLBCs, such as clinical presentation and early age of onset, resemble those of b...

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書誌詳細
主要な著者: Holstege, Henne, Horlings, Hugo M, Velds, Arno, Langerød, Anita, Børresen-Dale, Anne-Lise, van de Vijver, Marc J, Nederlof, Petra M, Jonkers, Jos
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002929/
https://ncbi.nlm.nih.gov/pubmed/21118481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-654
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