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KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data

BACKGROUND: Most approaches used to find recurrent or differential DNA Copy Number Alterations (CNA) in array Comparative Genomic Hybridization (aCGH) data from groups of tumour samples depend on the discretization of the aCGH data to gain, loss or no-change states. This causes loss of valuable biol...

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Detalhes bibliográficos
Main Authors: de Ronde, Jorma J, Klijn, Christiaan, Velds, Arno, Holstege, Henne, Reinders, Marcel JT, Jonkers, Jos, Wessels, Lodewyk FA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995794/
https://ncbi.nlm.nih.gov/pubmed/21070656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-298
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