Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

Triple negative breast cancers (TNBCs) have a relatively poor prognosis and cannot be effectively treated with current targeted therapies. We searched for genes that have the potential to be therapeutic targets by identifying genes consistently over-expressed when amplified. Fifty-six TNBCs were sub...

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Detalhes bibliográficos
Main Authors: Turner, Nicholas, Lambros, Maryou B, Horlings, Hugo M., Pearson, Alex, Sharpe, Rachel, Natrajan, Rachael, Geyer, Felipe C, van Kouwenhove, Marieke, Kreike, Bas, Mackay, Alan, Ashworth, Alan, van de Vijver, Marc J, Reis-Filho, Jorge S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852518/
https://ncbi.nlm.nih.gov/pubmed/20101236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.489
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