How I treat MSI cancers with advanced disease

Tekijä Kok, Marleen, Chalabi, Myriam, Haanen, John
Julkaisussa ESMO Open (2019)

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer

Tekijä Nederlof, Iris, Horlings, Hugo M., Curtis, Christina, Kok, Marleen
Julkaisussa Cancers (Basel) (2021)

Oestrogen receptor–co-factor–chromatin specificity in the transcriptional regulation of breast cancer

Tekijä Zwart, Wilbert, Theodorou, Vasiliki, Kok, Marleen, Canisius, Sander, Linn, Sabine, Carroll, Jason S
Julkaistu 2011

Oestrogen receptor–co-factor–chromatin specificity in the transcriptional regulation of breast cancer

Tekijä Zwart, Wilbert, Theodorou, Vasiliki, Kok, Marleen, Canisius, Sander, Linn, Sabine, Carroll, Jason S
Julkaistu 2011

Targeting immune checkpoints in breast cancer: an update of early results

Tekijä Solinas, Cinzia, Gombos, Andrea, Latifyan, Sofiya, Piccart-Gebhart, Martine, Kok, Marleen, Buisseret, Laurence
Julkaisussa ESMO Open (2017)

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13

Tekijä Bentin Toaldo, Cristiane, Alexi, Xanthippi, Beelen, Karin, Kok, Marleen, Hauptmann, Michael, Jansen, Maurice, Berns, Els, Neefjes, Jacques, Linn, Sabine, Michalides, Rob, Zwart, Wilbert
Julkaisussa BMC Cancer (2015)

A STING agonist given with OX40 receptor and PD-L1 modulators primes immunity and reduces tumor growth in tolerized mice

Tekijä Foote, Jeremy B., Kok, Marleen, Leatherman, James M., Armstrong, Todd D., Marcinkowski, Bridget C., Ojalvo, Laureen S., Kanne, David B., Jaffee, Elizabeth M., Dubensky, Thomas W., Emens, Leisha A.
Julkaisussa Cancer Immunol Res (2017)

The NFκB pathway promotes tamoxifen tolerance and disease recurrence in estrogen receptor positive breast cancers

Tekijä Kastrati, Irida, Joosten, Stacey E. P., Semina, Svetlana E., Alejo, Luis H., Brovkovych, Svitlana D., Stender, Joshua D., Horlings, Hugo M., Kok, Marleen, Alarid, Elaine T., Greene, Geoffrey L., Linn, Sabine C., Zwart, Wilbert, Frasor, Jonna
Julkaisussa Mol Cancer Res (2020)

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes

Tekijä Sobral-Leite, Marcelo, Salomon, Izhar, Opdam, Mark, Kruger, Dinja T., Beelen, Karin J., van der Noort, Vincent, van Vlierberghe, Ronald L. P., Blok, Erik J., Giardiello, Daniele, Sanders, Joyce, Van de Vijver, Koen, Horlings, Hugo M., Kuppen, Peter J. K., Linn, Sabine C., Schmidt, Marjanka K., Kok, Marleen
Julkaisussa Breast Cancer Res (2019)

Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy

Tekijä van Rossum, Annelot G.J., Kok, Marleen, McCool, Danielle, Opdam, Mark, Miltenburg, Nienke C., Mandjes, Ingrid A.M., van Leeuwen-Stok, Elise, Imholz, Alex L.T., Portielje, Johanneke E.A., Bos, Monique M.E.M., van Bochove, Aart, van Werkhoven, Erik, Schmidt, Marjanka K., Oosterkamp, Hendrika M., Linn, Sabine C.
Julkaisussa Oncotarget (2017)

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer

Tekijä Nederlof, Iris, De Bortoli, Davide, Bareche, Yacine, Nguyen, Bastien, de Maaker, Michiel, Hooijer, Gerrit K. J., Buisseret, Laurence, Kok, Marleen, Smid, Marcel, Van den Eynden, Gert G. G. M., Brinkman, Arie B., Hudecek, Jan, Koster, Jan, Sotiriou, Christos, Larsimont, Denis, Martens, John W. M., van de Vijver, Marc J., Horlings, Hugo M., Salgado, Roberto, Biganzoli, Elia, Desmedt, Christine
Julkaisussa Breast Cancer Res (2019)

Decreased expression of ABAT and STC2 hallmarks ER‐positive inflammatory breast cancer and endocrine therapy resistance in advanced disease

Tekijä Jansen, Maurice P.H.M., Sas, Leen, Sieuwerts, Anieta M., Van Cauwenberghe, Caroline, Ramirez-Ardila, Diana, Look, Maxime, Ruigrok-Ritstier, Kirsten, Finetti, Pascal, Bertucci, François, Timmermans, Mieke M., van Deurzen, Carolien H.M., Martens, John W.M., Simon, Iris, Roepman, Paul, Linn, Sabine C., van Dam, Peter, Kok, Marleen, Lardon, Filip, Vermeulen, Peter B., Foekens, John A., Dirix, Luc, Berns, Els M.J.J., Van Laere, Steven
Julkaisussa Mol Oncol (2015)

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival

Tekijä Sobral-Leite, Marcelo, Van de Vijver, Koen, Michaut, Magali, van der Linden, Rianne, Hooijer, Gerrit K.J., Horlings, Hugo M., Severson, Tesa M., Mulligan, Anna Marie, Weerasooriya, Nayana, Sanders, Joyce, Glas, Annuska M, Wehkamp, Diederik, Mittempergher, Lorenza, Kersten, Kelly, Cimino-Mathews, Ashley, Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, van de Vijver, Marc J., Bernards, Rene, Andrulis, Irene L., Kok, Marleen, de Visser, Karin E., Schmidt, Marjanka K.
Julkaisussa Oncoimmunology (2018)

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

Tekijä Hudeček, Jan, Voorwerk, Leonie, van Seijen, Maartje, Nederlof, Iris, de Maaker, Michiel, van den Berg, Jose, van de Vijver, Koen K., Sikorska, Karolina, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Michiels, Stefan, Symmans, William Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen M., Denkert, Carsten, Loibl, Sibylle, Loi, Sherene, Bartlett, John M. S., Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie C. U., Tutt, Andrew, Hall, Jacqueline A., Kos, Zuzana, Salgado, Roberto, Kok, Marleen, Horlings, Hugo M.
Julkaisussa NPJ Breast Cancer (2020)

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

Tekijä Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K., Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H., Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M., Horlings, Hugo M., Hudeček, Jan, Ciompi, Francesco, Moore, David A., Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K., Kirtani, Pawan, Chen, I-Chun, Braybrooke, Jeremy P., Pruneri, Giancarlo, Demaria, Sandra, Adams, Sylvia, Schnitt, Stuart J., Lakhani, Sunil R., Rojo, Federico, Comerma, Laura, Badve, Sunil S., Khojasteh, Mehrnoush, Symmans, W. Fraser, Sotiriou, Christos, Gonzalez-Ericsson, Paula, Pogue-Geile, Katherine L., Kim, Rim S., Rimm, David L., Viale, Giuseppe, Hewitt, Stephen M., Bartlett, John M. S., Penault-Llorca, Frédérique, Goel, Shom, Lien, Huang-Chun, Loibl, Sibylle, Kos, Zuzana, Loi, Sherene, Hanna, Matthew G., Michiels, Stefan, Kok, Marleen, Nielsen, Torsten O., Lazar, Alexander J., Bago-Horvath, Zsuzsanna, Kooreman, Loes F. S., van der Laak, Jeroen A. W. M., Saltz, Joel, Gallas, Brandon D., Kurkure, Uday, Barnes, Michael, Salgado, Roberto, Cooper, Lee A. D.
Julkaisussa NPJ Breast Cancer (2020)

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Tekijä Kos, Zuzana, Roblin, Elvire, Kim, Rim S., Michiels, Stefan, Gallas, Brandon D., Chen, Weijie, van de Vijver, Koen K., Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Symmans, W. Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen, Denkert, Carsten, Loibl, Sibylle, Luen, Stephen J., Bartlett, John M. S., Savas, Peter, Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie Chon U., Tutt, Andrew, Hall, Jacqueline A., Kok, Marleen, Horlings, Hugo M., Madabhushi, Anant, van der Laak, Jeroen, Ciompi, Francesco, Laenkholm, Anne-Vibeke, Bellolio, Enrique, Gruosso, Tina, Fox, Stephen B., Araya, Juan Carlos, Floris, Giuseppe, Hudeček, Jan, Voorwerk, Leonie, Beck, Andrew H., Kerner, Jen, Larsimont, Denis, Declercq, Sabine, Van den Eynden, Gert, Pusztai, Lajos, Ehinger, Anna, Yang, Wentao, AbdulJabbar, Khalid, Yuan, Yinyin, Singh, Rajendra, Hiley, Crispin, Bakir, Maise al, Lazar, Alexander J., Naber, Stephen, Wienert, Stephan, Castillo, Miluska, Curigliano, Giuseppe, Dieci, Maria-Vittoria, André, Fabrice, Swanton, Charles, Reis-Filho, Jorge, Sparano, Joseph, Balslev, Eva, Chen, I-Chun, Stovgaard, Elisabeth Ida Specht, Pogue-Geile, Katherine, Blenman, Kim R. M., Penault-Llorca, Frédérique, Schnitt, Stuart, Lakhani, Sunil R., Vincent-Salomon, Anne, Rojo, Federico, Braybrooke, Jeremy P., Hanna, Matthew G., Soler-Monsó, M. Teresa, Bethmann, Daniel, Castaneda, Carlos A., Willard-Gallo, Karen, Sharma, Ashish, Lien, Huang-Chun, Fineberg, Susan, Thagaard, Jeppe, Comerma, Laura, Gonzalez-Ericsson, Paula, Brogi, Edi, Loi, Sherene, Saltz, Joel, Klaushen, Frederick, Cooper, Lee, Amgad, Mohamed, Moore, David A., Salgado, Roberto
Julkaisussa NPJ Breast Cancer (2020)