Clinical Development of Listeria monocytogenes–Based Immunotherapies

Por Le, Dung T., Dubensky, Thomas W., Brockstedt, Dirk G.
Publicado em 2012

Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants

Por Dubensky, Thomas W., Kanne, David B., Leong, Meredith L.
Publicado em 2013

The host STING pathway at the interface of cancer and immunity

Por Corrales, Leticia, McWhirter, Sarah M., Dubensky, Thomas W., Gajewski, Thomas F.
Publicado no J Clin Invest (2016)

Enhancement of Tumor-specific Immune Response with Plasmid DNA Replicon Vectors

Por Leitner, Wolfgang W., Ying, Han, Driver, David A., Dubensky, Thomas W., Restifo, Nicholas P.
Publicado em 2000

Clinical experience with live-attenuated, double-deleted (LADD) listeria monocytogenes targeting mesothelin-expressing tumors

Por Brockstedt, Dirk G, Le, Dung T, Hassan, Raffit, Murphy, Aimee, Grous, John, Dubensky, Thomas W, Jaffee, Elizabeth M
Publicado em 2013

Antagonism of the STING pathway via activation of the AIM2 inflammasome by intracellular DNA

Por Corrales, Leticia, Woo, Seng-Ryong, Williams, Jason, McWhirter, Sarah M., Dubensky, Thomas W., Gajewski, Thomas F.
Publicado no J Immunol (2016)

Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity

Por Crimmins, Gregory T., Herskovits, Anat A., Rehder, Kai, Sivick, Kelsey E., Lauer, Peter, Dubensky, Thomas W., Portnoy, Daniel A.
Publicado em 2008

STING pathway activation stimulates potent immunity against acute myeloid leukemia

Por Curran, Emily, Chen, Xiufen, Corrales, Leticia, Kline, Douglas E., Dubensky, Thomas W., Duttagupta, Priyanka, Kortylewski, Marcin, Kline, Justin
Publicado no Cell Rep (2016)

Replicon Vectors Derived from Sindbis Virus and Semliki Forest Virus That Establish Persistent Replication in Host Cells

Por Perri, Silvia, Driver, David A., Gardner, Jason P., Sherrill, Scott, Belli, Barbara A., Dubensky, Thomas W., Polo, John M.
Publicado em 2000

Cytosolic Entry Controls CD8(+)-T-Cell Potency during Bacterial Infection

Por Bahjat, Keith S., Liu, Weiqun, Lemmens, Edward E., Schoenberger, Stephen P., Portnoy, Daniel A., Dubensky, Thomas W., Brockstedt, Dirk G.
Publicado em 2006

Impact of Preexisting Vector-Specific Immunity on Vaccine Potency: Characterization of Listeria monocytogenes-Specific Humoral and Cellular Immunity in Humans and Modeling Studies...

Por Leong, Meredith L., Hampl, Johannes, Liu, Weiqun, Mathur, Shruti, Bahjat, Keith S., Luckett, William, Dubensky, Thomas W., Brockstedt, Dirk G.
Publicado em 2009

Suppression of Cell-Mediated Immunity following Recognition of Phagosome-Confined Bacteria

Por Bahjat, Keith S., Meyer-Morse, Nicole, Lemmens, Edward E., Shugart, Jessica A., Dubensky, Thomas W., Brockstedt, Dirk G., Portnoy, Daniel A.
Publicado em 2009

Intratumoral injection of STING ligand promotes abscopal effect

Por Baird, Jason R, Dubensky, Thomas W, Kanne, David B, Friedman, David J, Cottam, Benjamin, Bambina, Shelly, Bahjat, Keith S, Crittenden, Marka, Gough, Michael
Publicado no J Immunother Cancer (2014)

Radiation therapy combined with novel STING-targeting oligonucleotides results in regression of established tumors

Por Baird, Jason R., Friedman, David, Cottam, Benjamin, Dubensky, Thomas W., Kanne, David B., Bambina, Shelly, Bahjat, Keith, Crittenden, Marka R., Gough, Michael J.
Publicado no Cancer Res (2015)

The Resistance of Retroviral Vectors Produced from Human Cells to Serum Inactivation In Vivo and In Vitro Is Primate Species Dependent

Por DePolo, Nicholas J., Harkleroad, Cataline E., Bodner, Mordechai, Watt, Andrew T., Anderson, Carol G., Greengard, Judith S., Murthy, Krishna K., Dubensky, Thomas W., Jolly, Douglas J.
Publicado em 1999

KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity

Por Skoberne, Mojca, Yewdall, Alice, Bahjat, Keith S., Godefroy, Emmanuelle, Lauer, Peter, Lemmens, Edward, Liu, Weiqun, Luckett, Will, Leong, Meredith, Dubensky, Thomas W., Brockstedt, Dirk G., Bhardwaj, Nina
Publicado em 2008

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

Por Brockstedt, Dirk G., Giedlin, Martin A., Leong, Meredith L., Bahjat, Keith S., Gao, Yi, Luckett, William, Liu, Weiqun, Cook, David N., Portnoy, Daniel A., Dubensky, Thomas W.
Publicado em 2004

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

Por Leitner, Wolfgang W., Hwang, Leroy N., Deveer, Michael J., Zhou, Aimin, Silverman, Robert H., Williams, Bryan R.G., Dubensky, Thomas W., Ying, Han, Restifo, Nicholas P.
Publicado em 2002

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

Por Wang, Guoshun, Slepushkin, Vladimir, Zabner, Joseph, Keshavjee, Shaf, Johnston, Julie C., Sauter, Sybille L., Jolly, Doug J., Dubensky, Thomas W., Davidson, Beverly L., McCray, Paul B.
Publicado em 1999

Attenuated Listeria monocytogenes Vectors Overcome Suppressive Plasma Factors During HIV Infection to Stimulate Myeloid Dendritic Cells to Promote Adaptive Immunity and Reactivatio...

Por Miller, Elizabeth A., Spadaccia, Meredith R., Norton, Thomas, Demmler, Morgan, Gopal, Ramya, O'Brien, Meagan, Landau, Nathaniel, Dubensky, Thomas W., Lauer, Peter, Brockstedt, Dirk G., Bhardwaj, Nina
Publicado no AIDS Res Hum Retroviruses (2015)