Radiation therapy combined with novel STING-targeting oligonucleotides results in regression of established tumors

Cytotoxic therapies prime adaptive immune responses to cancer by stimulating the release of tumor-associated antigens. However, the tumor microenvironment into which these antigens are released is typically immunosuppressed, blunting the ability to initiate immune responses. Recently, activation of...

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Foilsithe in:Cancer Res
Main Authors: Baird, Jason R., Friedman, David, Cottam, Benjamin, Dubensky, Thomas W., Kanne, David B., Bambina, Shelly, Bahjat, Keith, Crittenden, Marka R., Gough, Michael J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703500/
https://ncbi.nlm.nih.gov/pubmed/26567136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3619
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