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Amplifying IFNγ signaling in DC by CD11c-specific loss of SOCS1 increases innate immunity to infection while decreasing adaptive immunity
While prophylactic vaccines provide protective humoral immunity against infectious agents, vaccines that elicit potent CD8 T cell responses are valuable tools to shape and drive cellular immunity against cancer and intracellular infection. In particular, IFNγ-polarized cytotoxic CD8 T cell immunity...
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| Publicado no: | J Immunol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736417/ https://ncbi.nlm.nih.gov/pubmed/29150567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700909 |
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