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Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity
Radiation therapy is a source of tumor antigen release that has the potential to serve as an endogenous tumor vaccination event. In preclinical models radiation therapy synergizes with checkpoint inhibitors to cure tumors via CD8 T cell responses. To evaluate the immune response initiated by radiati...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934473/ https://ncbi.nlm.nih.gov/pubmed/29725089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25482-w |
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