Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity

Radiation therapy is a source of tumor antigen release that has the potential to serve as an endogenous tumor vaccination event. In preclinical models radiation therapy synergizes with checkpoint inhibitors to cure tumors via CD8 T cell responses. To evaluate the immune response initiated by radiati...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Crittenden, Marka R., Zebertavage, Lauren, Kramer, Gwen, Bambina, Shelly, Friedman, David, Troesch, Victoria, Blair, Tiffany, Baird, Jason R., Alice, Alejandro, Gough, Michael J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934473/
https://ncbi.nlm.nih.gov/pubmed/29725089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25482-w
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires