Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity

Radiation therapy is a source of tumor antigen release that has the potential to serve as an endogenous tumor vaccination event. In preclinical models radiation therapy synergizes with checkpoint inhibitors to cure tumors via CD8 T cell responses. To evaluate the immune response initiated by radiati...

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發表在:Sci Rep
Main Authors: Crittenden, Marka R., Zebertavage, Lauren, Kramer, Gwen, Bambina, Shelly, Friedman, David, Troesch, Victoria, Blair, Tiffany, Baird, Jason R., Alice, Alejandro, Gough, Michael J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934473/
https://ncbi.nlm.nih.gov/pubmed/29725089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25482-w
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