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STING pathway activation stimulates potent immunity against acute myeloid leukemia
Type I interferon (IFN), essential for spontaneous T cell priming against solid tumors, is generated through recognition of tumor DNA by STING. Interestingly, we observe that type I IFN is not elicited in animals with disseminated acute myeloid leukemia (AML). Further, survival of leukemia-bearing a...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116809/ https://ncbi.nlm.nih.gov/pubmed/27264175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.023 |
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