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Peripheral T-cell tolerance in hosts with acute myeloid leukemia

Our laboratory investigates the immune tolerance mechanisms promoted by acute myeloid leukemia (AML). In a murine AML model, we have observed that leukemia antigen-specific T cells are specifically deleted from the host, presumably following interactions with immature host antigen-presenting cells (...

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Detalhes bibliográficos
Main Authors: Chen, Xiufen, Kline, Douglas E, Kline, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812197/
https://ncbi.nlm.nih.gov/pubmed/24179704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25445
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