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Calreticulin promotes immunity and type I interferon-dependent survival in mice with acute myeloid leukemia

Exposure of cancer cells to particular chemotherapeutic agents or γ-irradiation induces a form of cell death that stimulates an immune response in mice. This “immunogenic cell death” requires calreticulin (CRT) translocation to the plasma membrane, which has been shown to promote cancer cell phagocy...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Chen, Xiufen, Fosco, Dominick, Kline, Douglas E., Kline, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414882/
https://ncbi.nlm.nih.gov/pubmed/28507789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1278332
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