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The Resistance of Retroviral Vectors Produced from Human Cells to Serum Inactivation In Vivo and In Vitro Is Primate Species Dependent

The ability to deliver genes as therapeutics requires an understanding of the vector pharmacokinetics similar to that required for conventional drugs. A first question is the half-life of the vector in the bloodstream. Retroviral vectors produced in certain human cell lines differ from vectors produ...

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Detalhes bibliográficos
Main Authors: DePolo, Nicholas J., Harkleroad, Cataline E., Bodner, Mordechai, Watt, Andrew T., Anderson, Carol G., Greengard, Judith S., Murthy, Krishna K., Dubensky, Thomas W., Jolly, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112755/
https://ncbi.nlm.nih.gov/pubmed/10400768
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