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Retroviral Vectors Produced in the Cytoplasmic Vaccinia Virus System Transduce Intron-Containing Genes

Introns and polyadenylation (pA) sites are known to improve transcript stability and nuclear-cytoplasmic transport and are normally present in efficient gene expression vectors. Standard retroviral vectors, however, do not allow the inclusion of such sequence elements, as mRNA processing at internal...

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Detalhes bibliográficos
Main Authors: Konetschny, C., Holzer, G. W., Falkner, F. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135843/
https://ncbi.nlm.nih.gov/pubmed/11773399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1236-1243.2002
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