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Retroviral Vectors Produced in the Cytoplasmic Vaccinia Virus System Transduce Intron-Containing Genes

Introns and polyadenylation (pA) sites are known to improve transcript stability and nuclear-cytoplasmic transport and are normally present in efficient gene expression vectors. Standard retroviral vectors, however, do not allow the inclusion of such sequence elements, as mRNA processing at internal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Konetschny, C., Holzer, G. W., Falkner, F. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135843/
https://ncbi.nlm.nih.gov/pubmed/11773399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1236-1243.2002
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