Retroviral Vectors Produced in the Cytoplasmic Vaccinia Virus System Transduce Intron-Containing Genes

Introns and polyadenylation (pA) sites are known to improve transcript stability and nuclear-cytoplasmic transport and are normally present in efficient gene expression vectors. Standard retroviral vectors, however, do not allow the inclusion of such sequence elements, as mRNA processing at internal...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Konetschny, C., Holzer, G. W., Falkner, F. G.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773399/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1236-1243.2002
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