Llwytho...

DNA Methylation of Helper Virus Increases Genetic Instability of Retroviral Vector Producer Cells

Retroviral vector producer cells (VPC) have been considered genetically stable. A clonal cell population exhibiting a uniform vector integration pattern is used for sustained vector production. Here, we observed that the vector copy number is increased and varied in a population of established LTKOS...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Young, Won-Bin, Lindberg, Gary L., Link, Charles J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC111818/
https://ncbi.nlm.nih.gov/pubmed/10708434
Tagiau: Ychwanegu Tag
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