DNA Methylation of Helper Virus Increases Genetic Instability of Retroviral Vector Producer Cells
Retroviral vector producer cells (VPC) have been considered genetically stable. A clonal cell population exhibiting a uniform vector integration pattern is used for sustained vector production. Here, we observed that the vector copy number is increased and varied in a population of established LTKOS...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3177-3187.2000 |
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