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Antagonism of the STING pathway via activation of the AIM2 inflammasome by intracellular DNA
Recent evidence has indicated that innate immune sensing of cytosolic DNA in dendritic cells via the host STING pathway is a major mechanism leading to spontaneous T cell responses against tumors. However, the impact of the other major pathway triggered by intracellular DNA, the AIM2 inflammasome, o...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800192/ https://ncbi.nlm.nih.gov/pubmed/26927800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502538 |
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