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The host STING pathway at the interface of cancer and immunity

A major subset of human cancers shows evidence for spontaneous adaptive immunity, which is reflected by the presence of infiltrating CD8(+) T cells specific for tumor antigens within the tumor microenvironment. This observation has raised the question of which innate immune sensing pathway might det...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Corrales, Leticia, McWhirter, Sarah M., Dubensky, Thomas W., Gajewski, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922692/
https://ncbi.nlm.nih.gov/pubmed/27367184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86892
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