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Listeria-based cancer vaccines that segregate immunogenicity from toxicity

The facultative intracellular bacterium Listeria monocytogenes is being developed as a cancer vaccine platform because of its ability to induce potent innate and adaptive immunity. For successful clinical application, it is essential to develop a Listeria platform strain that is safe yet retains the...

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Detalhes bibliográficos
Main Authors: Brockstedt, Dirk G., Giedlin, Martin A., Leong, Meredith L., Bahjat, Keith S., Gao, Yi, Luckett, William, Liu, Weiqun, Cook, David N., Portnoy, Daniel A., Dubensky, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518841/
https://ncbi.nlm.nih.gov/pubmed/15365184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406035101
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