Infiltration of CD8(+) T cells into tumor cell clusters in triple-negative breast cancer

Por Li, Xuefei, Gruosso, Tina, Zuo, Dongmei, Omeroglu, Atilla, Meterissian, Sarkis, Guiot, Marie-Christine, Salazar, Adam, Park, Morag, Levine, Herbert
Publicado no Proc Natl Acad Sci U S A (2019)

MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas

Por Gruosso, Tina, Garnier, Camille, Abelanet, Sophie, Kieffer, Yann, Lemesre, Vincent, Bellanger, Dorine, Bieche, Ivan, Marangoni, Elisabetta, Sastre-Garau, Xavier, Mieulet, Virginie, Mechta-Grigoriou, Fatima
Publicado no Nat Commun (2015)

Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach

Por Bareche, Yacine, Buisseret, Laurence, Gruosso, Tina, Girard, Edwina, Venet, David, Dupont, Floriane, Desmedt, Christine, Larsimont, Denis, Park, Morag, Rothé, Françoise, Stagg, John, Sotiriou, Christos
Publicado no J Natl Cancer Inst (2019)

HIV-1 vpr inhibits cytokinesis in human proximal tubule cells

Por Rosenstiel, Paul, Gruosso, Tina, Letourneau, Audrey, Chan, Justin, LeBlanc, Amanda, Husain, Mohammad, Najfeld, Vesna, Planelles, Vicente, D’Agati, Vivette, Klotman, Mary, Klotman, Paul E.
Publicado em 2008

Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients

Por Gruosso, Tina, Mieulet, Virginie, Cardon, Melissa, Bourachot, Brigitte, Kieffer, Yann, Devun, Flavien, Dubois, Thierry, Dutreix, Marie, Vincent‐Salomon, Anne, Miller, Kyle Malcolm, Mechta‐Grigoriou, Fatima
Publicado no EMBO Mol Med (2016)

The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway

Por Mui, Melissa Z., Zhou, Yiwang, Blanchette, Paola, Chughtai, Naila, Knight, Jennifer F., Gruosso, Tina, Papadakis, Andreas I., Huang, Sidong, Park, Morag, Gingras, Anne-Claude, Branton, Philip E.
Publicado no J Virol (2015)

Predicting Relapse in Patients With Triple Negative Breast Cancer (TNBC) Using a Deep-Learning Approach

Por Yu, Guangyuan, Li, Xuefei, He, Ting-Fang, Gruosso, Tina, Zuo, Dongmei, Souleimanova, Margarita, Ramos, Valentina Muñoz, Omeroglu, Atilla, Meterissian, Sarkis, Guiot, Marie-Christine, Yang, Li, Yuan, Yuan, Park, Morag, Lee, Peter P., Levine, Herbert
Publicado no Front Physiol (2020)

Inhibition of the stromal p38MAPK/MK2 pathway limits breast cancer metastases and chemotherapy-induced bone loss

Por Murali, Bhavna, Ren, Qihao, Luo, Xianmin, Faget, Douglas V., Wang, Chun, Johnson, Radia Marie, Gruosso, Tina, Flanagan, Kevin C., Fu, Yujie, Leahy, Kathleen, Alspach, Elise, Su, Xinming, Ross, Michael H., Burnette, Barry, Weilbaecher, Katherine N., Park, Morag, Mbalaviele, Gabriel, Monahan, Joseph B., Stewart, Sheila A.
Publicado no Cancer Res (2018)

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer

Por Knight, Jennifer F., Sung, Vanessa Y.C., Kuzmin, Elena, Couzens, Amber L., de Verteuil, Danielle A., Ratcliffe, Colin D.H., Coelho, Paula P., Johnson, Radia M., Samavarchi-Tehrani, Payman, Gruosso, Tina, Smith, Harvey W., Lee, Wontae, Saleh, Sadiq M., Zuo, Dongmei, Zhao, Hong, Guiot, Marie-Christine, Davis, Ryan R., Gregg, Jeffrey P., Moraes, Christopher, Gingras, Anne-Claude, Park, Morag
Publicado no Cell Rep (2018)

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

Por Gruosso, Tina, Gigoux, Mathieu, Manem, Venkata Satya Kumar, Bertos, Nicholas, Zuo, Dongmei, Perlitch, Irina, Saleh, Sadiq Mehdi Ismail, Zhao, Hong, Souleimanova, Margarita, Johnson, Radia Marie, Monette, Anne, Ramos, Valentina Muñoz, Hallett, Michael Trevor, Stagg, John, Lapointe, Réjean, Omeroglu, Atilla, Meterissian, Sarkis, Buisseret, Laurence, Van den Eynden, Gert, Salgado, Roberto, Guiot, Marie-Christine, Haibe-Kains, Benjamin, Park, Morag
Publicado no J Clin Invest (2019)

Tumor-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

Por Maller, Ori, Drain, Allison P., Barrett, Alexander S., Borgquist, Signe, Ruffell, Brian, Zakharevich, Igor, Pham, Thanh T., Gruosso, Tina, Kuasne, Hellen, Lakins, Johnathon N., Acerbi, Irene, Barnes, J. Matthew, Nemkov, Travis, Chauhan, Aastha, Gruenberg, Jessica, Nasir, Aqsa, Bjarnadottir, Olof, Werb, Zena, Kabos, Peter, Chen, Yunn-Yi, Hwang, E. Shelley, Park, Morag, Coussens, Lisa M., Nelson, Andrew C., Hansen, Kirk C., Weaver, Valerie M.
Publicado no Nat Mater (2020)

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Por Kos, Zuzana, Roblin, Elvire, Kim, Rim S., Michiels, Stefan, Gallas, Brandon D., Chen, Weijie, van de Vijver, Koen K., Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Symmans, W. Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen, Denkert, Carsten, Loibl, Sibylle, Luen, Stephen J., Bartlett, John M. S., Savas, Peter, Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie Chon U., Tutt, Andrew, Hall, Jacqueline A., Kok, Marleen, Horlings, Hugo M., Madabhushi, Anant, van der Laak, Jeroen, Ciompi, Francesco, Laenkholm, Anne-Vibeke, Bellolio, Enrique, Gruosso, Tina, Fox, Stephen B., Araya, Juan Carlos, Floris, Giuseppe, Hudeček, Jan, Voorwerk, Leonie, Beck, Andrew H., Kerner, Jen, Larsimont, Denis, Declercq, Sabine, Van den Eynden, Gert, Pusztai, Lajos, Ehinger, Anna, Yang, Wentao, AbdulJabbar, Khalid, Yuan, Yinyin, Singh, Rajendra, Hiley, Crispin, Bakir, Maise al, Lazar, Alexander J., Naber, Stephen, Wienert, Stephan, Castillo, Miluska, Curigliano, Giuseppe, Dieci, Maria-Vittoria, André, Fabrice, Swanton, Charles, Reis-Filho, Jorge, Sparano, Joseph, Balslev, Eva, Chen, I-Chun, Stovgaard, Elisabeth Ida Specht, Pogue-Geile, Katherine, Blenman, Kim R. M., Penault-Llorca, Frédérique, Schnitt, Stuart, Lakhani, Sunil R., Vincent-Salomon, Anne, Rojo, Federico, Braybrooke, Jeremy P., Hanna, Matthew G., Soler-Monsó, M. Teresa, Bethmann, Daniel, Castaneda, Carlos A., Willard-Gallo, Karen, Sharma, Ashish, Lien, Huang-Chun, Fineberg, Susan, Thagaard, Jeppe, Comerma, Laura, Gonzalez-Ericsson, Paula, Brogi, Edi, Loi, Sherene, Saltz, Joel, Klaushen, Frederick, Cooper, Lee, Amgad, Mohamed, Moore, David A., Salgado, Roberto
Publicado no NPJ Breast Cancer (2020)