HIV-1 vpr inhibits cytokinesis in human proximal tubule cells

HIV associated nephropathy (HIVAN) afflicts an estimated 1–3 million people worldwide and is a major cause of morbidity and mortality. Murine transgenic models have demonstrated that expression of HIV-1 genes in kidney cells results in characteristic HIVAN pathology: collapsing FSGS and microcystic...

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Main Authors: Rosenstiel, Paul, Gruosso, Tina, Letourneau, Audrey, Chan, Justin, LeBlanc, Amanda, Husain, Mohammad, Najfeld, Vesna, Planelles, Vicente, D’Agati, Vivette, Klotman, Mary, Klotman, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039560/
https://ncbi.nlm.nih.gov/pubmed/18614999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.303
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