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Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets

BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relati...

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Detalhes bibliográficos
Main Authors: Farazi, Thalia A, ten Hoeve, Jelle J, Brown, Miguel, Mihailovic, Aleksandra, Horlings, Hugo M, van de Vijver, Marc J, Tuschl, Thomas, Wessels, Lodewyk FA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053773/
https://ncbi.nlm.nih.gov/pubmed/24398324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r9
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