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Genome-wide identification of miRNA targets by PAR-CLIP
MiRNAs are short (20-23 nt) RNAs that are loaded into proteins of the Argonaute (AGO) family and guide them to partially complementary target sites on mRNAs, resulting in mRNA destabilization and/or translational repression. It is estimated that about 60% of the mammalian genes are potentially regul...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508682/ https://ncbi.nlm.nih.gov/pubmed/22926237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.08.006 |
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