Reactive metabolites of phenacetin and acetaminophen: a review

Por Hinson, Jack A.
Publicado em 1983

Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicity in vivo

Por Gujral, Jaspreet S, Hinson, Jack A, Jaeschke, Hartmut
Publicado em 2004

Mechanisms of Acetaminophen-Induced Liver Necrosis

Por Hinson, Jack A., Roberts, Dean W., James, Laura P.
Publicado em 2010

Reactive Nitrogen Species in Acetaminophen-Induced Mitochondrial Damage and Toxicity in Mouse Hepatocytes

Por Burke, Angela S., MacMillan-Crow, Lee Ann, Hinson, Jack A.
Publicado em 2010

Proinsulin Atypical Maturation and Disposal Induces Extensive Defects in Mouse Ins2(+/Akita) β-Cells

Por Yuan, Qingxin, Tang, Wei, Zhang, Xiaoping, Hinson, Jack A., Liu, Chao, Osei, Kwame, Wang, Jie
Publicado em 2012

Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite

Por Holthoff, Joseph H., Woodling, Kellie A., Doerge, Daniel R., Burns, Samuel T., Hinson, Jack A., Mayeux, Philip R.
Publicado em 2010

Acetaminophen hepatotoxicity and HIF-1α induction in mice occurs without hypoxia

Por Chaudhuri, Shubhra, McCullough, Sandra S., Hennings, Leah, Letzig, Lynda, Simpson, Pippa M., Hinson, Jack A., James, Laura P.
Publicado em 2011

Mouse Liver Protein Sulfhydryl Depletion after Acetaminophen Exposure

Por Yang, Xi, Greenhaw, James, Shi, Qiang, Roberts, Dean W., Hinson, Jack A., Muskhelishvili, Levan, Davis, Kelly, Salminen, William F.
Publicado em 2013

Indocyanine Green Clearance Varies as a Function of N-Acetylcysteine Treatment in a Murine Model of Acetaminophen Toxicity

Por Milesi-Hallé, Alessandra, Abdel-Rahman, Susan M., Brown, Aliza, McCullough, Sandra S., Letzig, Lynda, Hinson, Jack A., James, Laura P.
Publicado em 2010

Echinomycin Decreases Induction of Vascular Endothelial Growth Factor and Hepatocyte Regeneration in Acetaminophen Toxicity in Mice

Por Milesi-Hallé, Alessandra, McCullough, Sandra, Hinson, Jack A., Kurten, Richard C., Lamps, Laura W., Brown, Aliza, James, Laura P.
Publicado em 2011

The Neuronal Nitric Oxide Synthase Inhibitor NANT Blocks Acetaminophen Toxicity and Protein Nitration in Freshly Isolated Hepatocytes

Por Banerjee, Sudip, Melnyk, Stepan B., Krager, Kimberly J., Aykin-Burns, Nukhet, Letzig, Lynda G., James, Laura P., Hinson, Jack A
Publicado no Free Radic Biol Med (2015)

Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes

Por Banerjee, Sudip, Melnyk, Stepan B., Krager, Kimberly J., Aykin-Burns, Nukhet, McCullough, Sandra S., James, Laura P., Hinson, Jack A.
Publicado no Toxicol Rep (2017)

Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice()

Por Chaudhuri, Shubhra, McCullough, Sandra S., Hennings, Leah, Brown, Aliza T., Li, Shun-Hwa, Simpson, Pippa M., Hinson, Jack A., James, Laura P.
Publicado em 2012

Acylcarnitine Profiles in Acetaminophen Toxicity in the Mouse: Comparison to Toxicity, Metabolism and Hepatocyte Regeneration

Por Bhattacharyya, Sudeepa, Pence, Lisa, Beger, Richard, Chaudhuri, Shubhra, McCullough, Sandra, Yan, Ke, Simpson, Pippa, Hennings, Leah, Hinson, Jack, James, Laura
Publicado em 2013

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

Por James, Laura P., Letzig, Lynda, Simpson, Pippa M., Capparelli, Edmund, Roberts, Dean W., Hinson, Jack A., Davern, Timothy J., Lee, William M.
Publicado em 2009

Acetaminophen-Induced Hepatotoxicity in Mice Occurs with Inhibition of Activity and Nitration of Mitochondrial Manganese Superoxide Dismutase

Por Agarwal, Rakhee, MacMillan-Crow, Lee Ann, Rafferty, Tonya M., Saba, Hamida, Roberts, Dean W., Fifer, E. Kim, James, Laura P., Hinson, Jack A.
Publicado em 2011

Acetaminophen-Induced Hepatotoxicity and Protein Nitration in Neuronal Nitric-Oxide Synthase Knockout Mice

Por Agarwal, Rakhee, Hennings, Leah, Rafferty, Tonya M., Letzig, Lynda G., McCullough, Sandra, James, Laura P., MacMillan-Crow, Lee Ann, Hinson, Jack A.
Publicado em 2012

Human Recombinant Vascular Endothelial Growth Factor Reduces Necrosis and Enhances Hepatocyte Regeneration in a Mouse Model of Acetaminophen Toxicity

Por Donahower, Brian C., McCullough, Sandra S., Hennings, Leah, Simpson, Pippa M., Stowe, Cindy D., Saad, Ali G., Kurten, Richard C., Hinson, Jack A., James, Laura P.
Publicado em 2010

Changes in Mouse Liver Protein Glutathionylation after Acetaminophen Exposure

Por Yang, Xi, Greenhaw, James, Ali, Akhtar, Shi, Qiang, Roberts, Dean W., Hinson, Jack A., Muskhelishvili, Levan, Beger, Richard, Pence, Lisa M., Ando, Yosuke, Sun, Jinchun, Davis, Kelly, Salminen, William F.
Publicado em 2012

An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients with Acute Liver Injury or Failure: AcetaSTAT in Acute Liver Injury

Por Roberts, Dean W., Lee, William M., Hinson, Jack A., Bai, Shasha, Swearingen, Christopher J., Stravitz, R. Todd, Reuben, Adrian, Letzig, Lynda, Simpson, Pippa M., Rule, Jody, Fontana, Robert J., Ganger, Daniel, Reddy, K. Rajender, Liou, Iris, Fix, Oren, James, Laura P.
Publicado no Clin Gastroenterol Hepatol (2016)