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Mechanisms of Acetaminophen-Induced Liver Necrosis

Although considered safe at therapeutic doses, at higher doses, acetaminophen produces a centrilobular hepatic necrosis that can be fatal. Acetaminophen poisoning accounts for approximately one-half of all cases of acute liver failure in the United States and Great Britain today. The mechanism occur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hinson, Jack A., Roberts, Dean W., James, Laura P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836803/
https://ncbi.nlm.nih.gov/pubmed/20020268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-00663-0_12
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