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PUMA induction mediates acetaminophen-induced necrosis and liver injury
Acetaminophen (APAP) overdose is one of the leading causes of hepatotoxicity and acute liver failure in the United States. Accumulating evidence suggests that hepatocyte necrosis plays a critical role in APAP-induced liver injury. However, the mechanisms of APAP-induced necrosis and liver injury are...
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| Опубликовано в: : | Hepatology |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461480/ https://ncbi.nlm.nih.gov/pubmed/30552702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30422 |
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