PUMA induction mediates acetaminophen-induced necrosis and liver injury

Acetaminophen (APAP) overdose is one of the leading causes of hepatotoxicity and acute liver failure in the United States. Accumulating evidence suggests that hepatocyte necrosis plays a critical role in APAP-induced liver injury. However, the mechanisms of APAP-induced necrosis and liver injury are...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hepatology
Päätekijät: Chen, Dongshi, Ni, Hong-Min, Wang, Lei, Ma, Xiaowen, Yu, Jian, Ding, Wen-Xing, Zhang, Lin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461480/
https://ncbi.nlm.nih.gov/pubmed/30552702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30422
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