PUMA induction mediates acetaminophen-induced necrosis and liver injury

Acetaminophen (APAP) overdose is one of the leading causes of hepatotoxicity and acute liver failure in the United States. Accumulating evidence suggests that hepatocyte necrosis plays a critical role in APAP-induced liver injury. However, the mechanisms of APAP-induced necrosis and liver injury are...

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Udgivet i:Hepatology
Main Authors: Chen, Dongshi, Ni, Hong-Min, Wang, Lei, Ma, Xiaowen, Yu, Jian, Ding, Wen-Xing, Zhang, Lin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461480/
https://ncbi.nlm.nih.gov/pubmed/30552702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30422
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