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Role and Mechanisms of Autophagy in Acetaminophen-induced Liver Injury

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the United States and many other countries. Although the metabolism and pathogenesis of APAP has been extensively investigated for decades, the mechanisms by which APAP induces liver injury are incompletely known, whi...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Chao, Xiaojuan, Wang, Hua, Jaeschke, Hartmut, Ding, Wen-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105454/
https://ncbi.nlm.nih.gov/pubmed/29682868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13866
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