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Role and Mechanisms of Autophagy in Acetaminophen-induced Liver Injury

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the United States and many other countries. Although the metabolism and pathogenesis of APAP has been extensively investigated for decades, the mechanisms by which APAP induces liver injury are incompletely known, whi...

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Vydáno v:Liver Int
Hlavní autoři: Chao, Xiaojuan, Wang, Hua, Jaeschke, Hartmut, Ding, Wen-Xing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105454/
https://ncbi.nlm.nih.gov/pubmed/29682868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13866
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