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Role and Mechanisms of Autophagy in Acetaminophen-induced Liver Injury

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the United States and many other countries. Although the metabolism and pathogenesis of APAP has been extensively investigated for decades, the mechanisms by which APAP induces liver injury are incompletely known, whi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Liver Int
Hauptverfasser: Chao, Xiaojuan, Wang, Hua, Jaeschke, Hartmut, Ding, Wen-Xing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105454/
https://ncbi.nlm.nih.gov/pubmed/29682868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13866
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