Echinomycin Decreases Induction of Vascular Endothelial Growth Factor and Hepatocyte Regeneration in Acetaminophen Toxicity in Mice

Up-regulation of vascular endothelial growth factor (VEGF) is important to hepatocyte regeneration in the late stages of acetaminophen (APAP) toxicity in the mouse. The following study was conducted to examine the relationship of hypoxia inducible factor 1α (HIF-1α) to VEGF and hepatocyte regenerati...

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Hauptverfasser: Milesi-Hallé, Alessandra, McCullough, Sandra, Hinson, Jack A., Kurten, Richard C., Lamps, Laura W., Brown, Aliza, James, Laura P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289727/
https://ncbi.nlm.nih.gov/pubmed/21985601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-7843.2011.00812.x
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