Indocyanine Green Clearance Varies as a Function of N-Acetylcysteine Treatment in a Murine Model of Acetaminophen Toxicity

Standard assays to assess acetaminophen (APAP) toxicity in animal models include determination of ALT (alanine aminotransferase) levels and examination of histopathology of liver sections. However, these assays do not reflect the functional capacity of the injured liver. To examine a functional mark...

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Main Authors: Milesi-Hallé, Alessandra, Abdel-Rahman, Susan M., Brown, Aliza, McCullough, Sandra S., Letzig, Lynda, Hinson, Jack A., James, Laura P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046031/
https://ncbi.nlm.nih.gov/pubmed/21145883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.12.001
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