Acetaminophen protein adduct formation following low dose acetaminophen exposure: comparison of immediate release vs. extended release formulations

מאת James, Laura P., Chiew, Angela, Abdel-Rahman, Susan M., Letzig, Lynda, Graudins, Andis, Day, Peter, Roberts, Dean
יצא לאור 2012

Acetaminophen hepatotoxicity and HIF-1α induction in mice occurs without hypoxia

מאת Chaudhuri, Shubhra, McCullough, Sandra S., Hennings, Leah, Letzig, Lynda, Simpson, Pippa M., Hinson, Jack A., James, Laura P.
יצא לאור 2011

Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity

מאת James, Laura, Yan, Ke, Pence, Lisa, Simpson, Pippa, Bhattacharyya, Sudeepa, Gill, Pritmohinder, Letzig, Lynda, Kearns, Gregory, Beger, Richard
הוצא לאור ב PLoS One (2015)

Cooperativity in CYP2E1 Metabolism of Acetaminophen and Styrene Mixtures

מאת Hartman, Jessica H., Letzig, Lynda G., Robertsc, Dean W., James, Laura P., Fifer, E. Kim, Miller, Grover P.
הוצא לאור ב Biochem Pharmacol (2015)

MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

מאת Gill, Pritmohinder, Bhattacharyya, Sudeepa, McCullough, Sandra, Letzig, Lynda, Mishra, Prasun J., Luo, Chunqiao, Dweep, Harsh, James, Laura
הוצא לאור ב Sci Rep (2017)

Indocyanine Green Clearance Varies as a Function of N-Acetylcysteine Treatment in a Murine Model of Acetaminophen Toxicity

מאת Milesi-Hallé, Alessandra, Abdel-Rahman, Susan M., Brown, Aliza, McCullough, Sandra S., Letzig, Lynda, Hinson, Jack A., James, Laura P.
יצא לאור 2010

The Neuronal Nitric Oxide Synthase Inhibitor NANT Blocks Acetaminophen Toxicity and Protein Nitration in Freshly Isolated Hepatocytes

מאת Banerjee, Sudip, Melnyk, Stepan B., Krager, Kimberly J., Aykin-Burns, Nukhet, Letzig, Lynda G., James, Laura P., Hinson, Jack A
הוצא לאור ב Free Radic Biol Med (2015)

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

מאת James, Laura P., Letzig, Lynda, Simpson, Pippa M., Capparelli, Edmund, Roberts, Dean W., Hinson, Jack A., Davern, Timothy J., Lee, William M.
יצא לאור 2009

Acetaminophen-Induced Hepatotoxicity and Protein Nitration in Neuronal Nitric-Oxide Synthase Knockout Mice

מאת Agarwal, Rakhee, Hennings, Leah, Rafferty, Tonya M., Letzig, Lynda G., McCullough, Sandra, James, Laura P., MacMillan-Crow, Lee Ann, Hinson, Jack A.
יצא לאור 2012

Essential Role of Protein-tyrosine Phosphatase 1B in the Modulation of Insulin Signaling by Acetaminophen in Hepatocytes

מאת Mobasher, Maysa Ahmed, de Toro-Martín, Juan, González-Rodríguez, Águeda, Ramos, Sonia, Letzig, Lynda G., James, Laura P., Muntané, Jordi, Álvarez, Carmen, Valverde, Ángela M.
יצא לאור 2014

A Cytochrome P450–Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes

מאת Miyakawa, Kazuhisa, Albee, Ryan, Letzig, Lynda G., Lehner, Andreas F., Scott, Michael A., Buchweitz, John P., James, Laura P., Ganey, Patricia E., Roth, Robert A.
הוצא לאור ב J Pharmacol Exp Ther (2015)

Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose

מאת Bhattacharyya, Sudeepa, Pence, Lisa, Yan, Ke, Gill, Pritmohinder, Luo, Chunqiao, Letzig, Lynda G., Simpson, Pippa M., Kearns, Gregory L., Beger, Richard D., James, Laura P.
הוצא לאור ב Toxicol Rep (2016)

Targeted liquid chromatography–mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children

מאת Bhattacharyya, Sudeepa, Yan, Ke, Pence, Lisa, Simpson, Pippa M, Gill, Pritmohinder, Letzig, Lynda G, Beger, Richard D, Sullivan, Janice E, Kearns, Gregory L, Reed, Michael D, Marshall, James D, Van Den Anker, John N, James, Laura P
יצא לאור 2014

An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients with Acute Liver Injury or Failure: AcetaSTAT in Acute Liver Injury

מאת Roberts, Dean W., Lee, William M., Hinson, Jack A., Bai, Shasha, Swearingen, Christopher J., Stravitz, R. Todd, Reuben, Adrian, Letzig, Lynda, Simpson, Pippa M., Rule, Jody, Fontana, Robert J., Ganger, Daniel, Reddy, K. Rajender, Liou, Iris, Fix, Oren, James, Laura P.
הוצא לאור ב Clin Gastroenterol Hepatol (2016)

Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer

מאת Sun, Xuxu, Wang, Sam C., Wei, Yonglong, Luo, Xin, Jia, Yuemeng, Li, Lin, Gopal, Purva, Zhu, Min, Nassour, Ibrahim, Chuang, Jen-Chieh, Maples, Thomas, Celen, Cemre, Nguyen, Liem H., Wu, Linwei, Fu, Shunjun, Li, Weiping, Hui, Lijian, Tian, Feng, Ji, Yuan, Zhang, Shuyuan, Sorouri, Mahsa, Hwang, Tae Hyun, Letzig, Lynda, James, Laura, Wang, Zixi, Yopp, Adam, Singal, Amit G., Zhu, Hao
הוצא לאור ב Cancer Cell (2017)

Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer

מאת Sun, Xuxu, Wang, Sam C., Wei, Yonglong, Luo, Xin, Jia, Yuemeng, Li, Lin, Gopal, Purva, Zhu, Min, Nassour, Ibrahim, Chuang, Jen-Chieh, Maples, Thomas, Celen, Cemre, Nguyen, Liem H., Wu, Linwei, Fu, Shunjun, Li, Weiping, Hui, Lijian, Tian, Feng, Ji, Yuan, Zhang, Shuyuan, Sorouri, Mahsa, Hwang, Tae Hyun, Letzig, Lynda, James, Laura, Wang, Zixi, Yopp, Adam C., Singal, Amit G., Zhu, Hao
הוצא לאור ב Cancer Cell (2018)