An Approach to Evaluation of the Effect of Bioremediation on Biological Activity of Environmental Contaminants: Dechlorination of Polychlorinated Biphenyls

Por Ganey, Patricia E., Boyd, Steven A.
Publicado em 2005

Intrinsic versus Idiosyncratic Drug-Induced Hepatotoxicity—Two Villains or One?

Por Roth, Robert A., Ganey, Patricia E.
Publicado em 2010

Complement Activation in Acetaminophen-Induced Liver Injury in Mice

Por Singhal, Rohit, Ganey, Patricia E., Roth, Robert A.
Publicado em 2012

Tumor Necrosis Factorα Is a Proximal Mediator of Synergistic Hepatotoxicity from Trovafloxacin/Lipopolysaccharide Coexposure

Por Shaw, Patrick J., Ganey, Patricia E., Roth, Robert A.
Publicado em 2009

Trovafloxacin Enhances the Inflammatory Response to a Gram-Negative or a Gram-Positive Bacterial Stimulus, Resulting in Neutrophil-Dependent Liver Injury in Mice

Por Shaw, Patrick J., Ganey, Patricia E., Roth, Robert A.
Publicado em 2009

Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin Hepatotoxicity

Por Shaw, Patrick J., Ganey, Patricia E., Roth, Robert A.
Publicado em 2010

Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α

Por Sparkenbaugh, Erica M., Ganey, Patricia E., Roth, Robert A.
Publicado em 2012

2, 3, 7, 8-TCDD enhances the sensitivity of mice to concanavalin A immune-mediated liver injury

Por Fullerton, Aaron M., Roth, Robert A., Ganey, Patricia E.
Publicado em 2012

Pretreatment With TCDD Exacerbates Liver Injury From Concanavalin A: Critical Role for NK Cells

Por Fullerton, Aaron M., Roth, Robert A., Ganey, Patricia E.
Publicado em 2013

Tumor Necrosis Factor-alpha Potentiates the Cytotoxicity of Amiodarone in Hepa1c1c7 Cells: Roles of Caspase Activation and Oxidative Stress

Por Lu, Jingtao, Miyakawa, Kazuhisa, Roth, Robert A., Ganey, Patricia E.
Publicado em 2013

Roles of the Hemostatic System and Neutrophils in Liver Injury From Co-exposure to Amiodarone and Lipopolysaccharide

Por Lu, Jingtao, Roth, Robert A., Malle, Ernst, Ganey, Patricia E.
Publicado em 2013

2,2′,4,4′-Tetrachlorobiphenyl Upregulates Cyclooxygenase-2 in HL-60 cells via p38 Mitogen-Activated Protein Kinase and NF-κB

Por Bezdecny, Steven A., Karmaus, Peer, Roth, Robert A., Ganey, Patricia E.
Publicado em 2007

Inflammatory Stress and Idiosyncratic Hepatotoxicity: Hints from Animal Models

Por Deng, Xiaomin, Luyendyk, James P., Ganey, Patricia E., Roth, Robert A.
Publicado em 2009

Natural Killer Cells Mediate Severe Liver Injury in a Murine Model of Halothane Hepatitis

Por Dugan, Christine M., Fullerton, Aaron M., Roth, Robert A., Ganey, Patricia E.
Publicado em 2011

Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury

Por Zou, Wei, Roth, Robert A., Younis, Husam S., Malle, Ernst, Ganey, Patricia E.
Publicado em 2011

Trovafloxacin Potentiation of Lipopolysaccharide-Induced Tumor Necrosis Factor Release from RAW 264.7 Cells Requires Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kina...

Por Poulsen, Kyle L., Albee, Ryan P., Ganey, Patricia E., Roth, Robert A.
Publicado em 2014

Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment

Por Zou, Wei, Roth, Robert A., Younis, Husam S., Burgoon, Lyle D., Ganey, Patricia E.
Publicado em 2010

A Mouse Model of Severe Halothane Hepatitis Based on Human Risk Factors

Por Dugan, Christine M., MacDonald, Allen E., Roth, Robert A., Ganey, Patricia E.
Publicado em 2010

Hepatotoxic Interaction of Sulindac with Lipopolysaccharide: Role of the Hemostatic System

Por Zou, Wei, Devi, Sachin S., Sparkenbaugh, Erica, Younis, Husam S., Roth, Robert A., Ganey, Patricia E.
Publicado em 2009

Amiodarone Exposure During Modest Inflammation Induces Idiosyncrasy-like Liver Injury in Rats: Role of Tumor Necrosis Factor-alpha

Por Lu, Jingtao, Jones, A. Daniel, Harkema, Jack R., Roth, Robert A., Ganey, Patricia E.
Publicado em 2012