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Natural Killer Cells Mediate Severe Liver Injury in a Murine Model of Halothane Hepatitis
Severe halothane (HAL)-induced hepatotoxicity occurs in one in 6000–30,000 patients by an unknown mechanism. Female sex is a risk factor in humans and rodents. We tested the hypothesis that a sex difference in natural killer (NK) cell activity contributes to HAL-induced liver injury. HAL (15 mmol/kg...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061480/ https://ncbi.nlm.nih.gov/pubmed/21245496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr005 |
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