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Complement Activation in Acetaminophen-Induced Liver Injury in Mice
Overdose with acetaminophen (APAP) results in acute liver failure in humans and experimental animals. Complement comprises more than 30 proteins that can participate in tissue injury and/or repair, but the role of complement activation in APAP-induced hepatotoxicity has not been evaluated. Treatment...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336815/ https://ncbi.nlm.nih.gov/pubmed/22319198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.189837 |
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