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Roles of the Hemostatic System and Neutrophils in Liver Injury From Co-exposure to Amiodarone and Lipopolysaccharide

It has been demonstrated that co-treatment of rats with amiodarone (AMD) and bacterial lipopolysaccharide (LPS) produces idiosyncrasy-like liver injury. In this study, the hypothesis that the hemostatic system and neutrophils contribute to AMD/LPS-induced liver injury was explored. Rats were treated...

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Detalhes bibliográficos
Main Authors: Lu, Jingtao, Roth, Robert A., Malle, Ernst, Ganey, Patricia E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829566/
https://ncbi.nlm.nih.gov/pubmed/23912913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft170
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