Targeted liquid chromatography–mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children

AIM: Long-chain acylcarnitines have been postulated to be sensitive biomarkers of acetaminophen (APAP)-induced hepatotoxicity in mouse models. In the following study, the relationship of acylcarnitines with other known indicators of APAP toxicity was examined in children receiving low-dose (therapeu...

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Główni autorzy: Bhattacharyya, Sudeepa, Yan, Ke, Pence, Lisa, Simpson, Pippa M, Gill, Pritmohinder, Letzig, Lynda G, Beger, Richard D, Sullivan, Janice E, Kearns, Gregory L, Reed, Michael D, Marshall, James D, Van Den Anker, John N, James, Laura P
Format: Artigo
Język:Inglês
Wydane: 2014
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125006/
https://ncbi.nlm.nih.gov/pubmed/24521011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/bmm.13.150
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