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Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity

Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury. The relationship of individual bile acids to indicators of oxidative drug metabolism (aceta...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: James, Laura, Yan, Ke, Pence, Lisa, Simpson, Pippa, Bhattacharyya, Sudeepa, Gill, Pritmohinder, Letzig, Lynda, Kearns, Gregory, Beger, Richard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514842/
https://ncbi.nlm.nih.gov/pubmed/26208104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131010
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