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Reactive metabolites of phenacetin and acetaminophen: a review
Phenacetin can be metabolized to reactive metabolites by a variety of mechanisms. (1) Phenacetin can be N-hydroxylated, and the resulting N-hydroxyphenacetin can be sulfated or glucuronidated. Whereas phenacetin N-O sulfate immediately rearranges to form a reactive metabolite which may covalently bi...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1983
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569121/ https://ncbi.nlm.nih.gov/pubmed/6339229 |
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