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Reactive metabolites of phenacetin and acetaminophen: a review

Phenacetin can be metabolized to reactive metabolites by a variety of mechanisms. (1) Phenacetin can be N-hydroxylated, and the resulting N-hydroxyphenacetin can be sulfated or glucuronidated. Whereas phenacetin N-O sulfate immediately rearranges to form a reactive metabolite which may covalently bi...

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Bibliografiske detaljer
Hovedforfatter: Hinson, Jack A.
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569121/
https://ncbi.nlm.nih.gov/pubmed/6339229
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