Pancreatic neurogenin 3-expressing cells are unipotent islet precursors

Por Desgraz, Renaud, Herrera, Pedro L.
Publicado em 2009

Regeneration of Pancreatic Insulin-Producing Cells By In Situ Adaptive Cell Conversion

Por Chera, Simona, Herrera, Pedro L.
Publicado no Curr Opin Genet Dev (2016)

Stress-Induced Adaptive Islet Cell Identity Changes

Por Cigliola, Valentina, Thorel, Fabrizio, Chera, Simona, Herrera, Pedro L.
Publicado no Diabetes Obes Metab (2016)

Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis

Por Damond, Nicolas, Thorel, Fabrizio, Kim, Seung K., Herrera, Pedro L.
Publicado no Int J Biochem Cell Biol (2017)

Transgenic Overexpression of the Transcription Factor Nkx6.1 in β-Cells of Mice Does Not Increase β-Cell Proliferation, β-Cell Mass, or Improve Glucose Clearance

Por Schaffer, Ashleigh E., Yang, Almira J., Thorel, Fabrizio, Herrera, Pedro L., Sander, Maike
Publicado em 2011

Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas

Por Lu, Yarong, Ponton, André, Okamoto, Hiroshi, Takasawa, Shin, Herrera, Pedro L., Liu, Jun-Li
Publicado em 2006

Conversion of Adult Pancreatic α-cells to β-cells After Extreme β-cell Loss

Por Thorel, Fabrizio, Népote, Virginie, Avril, Isabelle, Kohno, Kenji, Desgraz, Renaud, Chera, Simona, Herrera, Pedro L.
Publicado em 2010

Progenitor cell domains in the developing and adult pancreas

Por Kopp, Janel L, Dubois, Claire L, Hao, Ergeng, Thorel, Fabrizio, Herrera, Pedro L, Sander, Maike
Publicado em 2011

Context-specific α-to-β-cell reprogramming by forced Pdx1 expression

Por Yang, Yu-Ping, Thorel, Fabrizio, Boyer, Daniel F., Herrera, Pedro L., Wright, Christopher V.E.
Publicado em 2011

Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression

Por Collombat, Patrick, Hecksher-Sørensen, Jacob, Krull, Jens, Berger, Joachim, Riedel, Dietmar, Herrera, Pedro L., Serup, Palle, Mansouri, Ahmed
Publicado em 2007

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

Por Thorel, Fabrizio, Damond, Nicolas, Chera, Simona, Wiederkehr, Andreas, Thorens, Bernard, Meda, Paolo, Wollheim, Claes B., Herrera, Pedro L.
Publicado em 2011

In Situ Electrophysiological Examination of Pancreatic α Cells in the Streptozotocin-Induced Diabetes Model, Revealing the Cellular Basis of Glucagon Hypersecretion

Por Huang, Ya-Chi, Rupnik, Marjan S., Karimian, Negar, Herrera, Pedro L., Gilon, Patrick, Feng, Zhong-Ping, Gaisano, Herbert Y.
Publicado em 2013

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist

Por Damond, Nicolas, Thorel, Fabrizio, Moyers, Julie S, Charron, Maureen J, Vuguin, Patricia M, Powers, Alvin C, Herrera, Pedro L
Publicado no eLife (2016)

Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes

Por van Krieken, Pim P., Dicker, Andrea, Eriksson, Maria, Herrera, Pedro L., Ahlgren, Ulf, Berggren, Per-Olof, Ilegems, Erwin
Publicado no Sci Rep (2017)

Nogo-A Downregulation Improves Insulin Secretion in Mice

Por Bonal, Claire B., Baronnier, Delphine E., Pot, Caroline, Benkhoucha, Mahdia, Schwab, Martin E., Lalive, Patrice H., Herrera, Pedro L.
Publicado em 2013

Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development

Por Supale, Sachin, Thorel, Fabrizio, Merkwirth, Carsten, Gjinovci, Asllan, Herrera, Pedro L., Scorrano, Luca, Meda, Paolo, Langer, Thomas, Maechler, Pierre
Publicado em 2013

Connective Tissue Growth Factor Modulates Adult β-Cell Maturity and Proliferation to Promote β-Cell Regeneration in Mice

Por Riley, Kimberly G., Pasek, Raymond C., Maulis, Matthew F., Peek, Jennifer, Thorel, Fabrizio, Brigstock, David R., Herrera, Pedro L., Gannon, Maureen
Publicado no Diabetes (2015)

The Transcription Factor Rfx3 Regulates β-Cell Differentiation, Function, and Glucokinase Expression

Por Ait-Lounis, Aouatef, Bonal, Claire, Seguín-Estévez, Queralt, Schmid, Christoph D., Bucher, Philipp, Herrera, Pedro L., Durand, Bénédicte, Meda, Paolo, Reith, Walter
Publicado em 2010

Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rg(null) RIP-DTR mice engrafted wi...

Por Yang, Chaoxing, Loehn, Matthias, Jurczyk, Agata, Przewozniak, Natalia, Leehy, Linda, Herrera, Pedro L, Shultz, Leonard D, Greiner, Dale L, Harlan, David M, Bortell, Rita
Publicado no Diabetes Metab Syndr Obes (2015)

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion

Por Solomou, Antonia, Meur, Gargi, Bellomo, Elisa, Hodson, David J., Tomas, Alejandra, Migrenne Li, Stéphanie, Philippe, Erwann, Herrera, Pedro L., Magnan, Christophe, Rutter, Guy A.
Publicado no J Biol Chem (2015)