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Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis
In addition to β-cells, pancreatic islets contain α- and δ-cells, which respectively produce glucagon and somatostatin. The reprogramming of these two endocrine cell types into insulin producers, as observed after a massive β-cell ablation in mice, may help restoring a functional β-cell mass in type...
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| Publicado no: | Int J Biochem Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494274/ https://ncbi.nlm.nih.gov/pubmed/28119131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2017.01.008 |
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