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Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression
Aristaless-related homeobox (Arx) was recently demonstrated to be involved in pancreatic α cell fate specification while simultaneously repressing the β and δ cell lineages. To establish whether Arx is not only necessary, but also sufficient to instruct the α cell fate in endocrine progenitors, we u...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1839241/ https://ncbi.nlm.nih.gov/pubmed/17404619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29115 |
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