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The Transcription Factor Rfx3 Regulates β-Cell Differentiation, Function, and Glucokinase Expression
OBJECTIVE: Pancreatic islets of perinatal mice lacking the transcription factor Rfx3 exhibit a marked reduction in insulin-producing β-cells. The objective of this work was to unravel the cellular and molecular mechanisms underlying this deficiency. RESEARCH DESIGN AND METHODS: Immunofluorescence st...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889767/ https://ncbi.nlm.nih.gov/pubmed/20413507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0986 |
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