To be or not to be

nork Zhang, Zhe, Hessmann, Elisabeth
Argitaratua izan da eLife (2018)

Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?

nork Hessmann, Elisabeth, Johnsen, Steven A, Siveke, Jens T, Ellenrieder, Volker
Argitaratua izan da Gut (2017)

Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression

nork Hasselluhn, Marie C., Schmidt, Geske E., Ellenrieder, Volker, Johnsen, Steven A., Hessmann, Elisabeth
Argitaratua izan da Cell Death Dis (2019)

Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models

nork Goetze, Robert-Guenther, Buchholz, Soeren M., Patil, Shilpa, Petzold, Golo, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht
Argitaratua izan da J Vis Exp (2018)

NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation

nork Hessmann, Elisabeth, Zhang, Jin-San, Chen, Nai-Ming, Hasselluhn, Marie, Liou, Geou-Yarh, Storz, Peter, Ellenrieder, Volker, Billadeau, Daniel D., Koenig, Alexander
Argitaratua izan da Stem Cells Int (2016)

Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer

nork Goetze, Robert G., Buchholz, Soeren M., Ou, Ning, Zhang, Qinrong, Patil, Shilpa, Schirmer, Markus, Singh, Shiv K., Ellenrieder, Volker, Hessmann, Elisabeth, Lu, Qing-Bin, Neesse, Albrecht
Argitaratua izan da Cells (2019)

Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer

nork Buchholz, Soeren M., Goetze, Robert G., Singh, Shiv K., Ammer-Herrmenau, Christoph, Richards, Frances M., Jodrell, Duncan I., Buchholz, Malte, Michl, Patrick, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht
Argitaratua izan da Cancers (Basel) (2020)

SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer

nork Ramu, Iswarya, Buchholz, Sören M., Patzak, Melanie S., Goetze, Robert G., Singh, Shiv K., Richards, Frances M., Jodrell, Duncan I., Sipos, Bence, Ströbel, Philipp, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht
Argitaratua izan da EBioMedicine (2019)

Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

nork Mishra, Vivek Kumar, Wegwitz, Florian, Kosinsky, Robyn Laura, Sen, Madhobi, Baumgartner, Roland, Wulff, Tanja, Siveke, Jens T., Schildhaus, Hans-Ulrich, Najafova, Zeynab, Kari, Vijayalakshmi, Kohlhof, Hella, Hessmann, Elisabeth, Johnsen, Steven A.
Argitaratua izan da Nucleic Acids Res (2017)

Nuclear factor of activated T-cells, NFATC1, governs FLT3(ITD)-driven hematopoietic stem cell transformation and a poor prognosis in AML

nork Solovey, Maria, Wang, Ying, Michel, Christian, Metzeler, Klaus H., Herold, Tobias, Göthert, Joachim R., Ellenrieder, Volker, Hessmann, Elisabeth, Gattenlöhner, Stefan, Neubauer, Andreas, Pavlinic, Dinko, Benes, Vladimir, Rupp, Oliver, Burchert, Andreas
Argitaratua izan da J Hematol Oncol (2019)

STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

nork Kutschat, Ana P., Hamdan, Feda H., Wang, Xin, Wixom, Alexander Q., Najafova, Zeynab, Gibhardt, Christine S., Kopp, Waltraut, Gaedcke, Jochen, Ströbel, Philipp, Ellenrieder, Volker, Bogeski, Ivan, Hessmann, Elisabeth, Johnsen, Steven A.
Argitaratua izan da Cancer Res (2021)

NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas

nork Chen, Nai-Ming, Singh, Garima, Koenig, Alexander, Liou, Geou-Yarh, Storz, Peter, Zhang, Jin-San, Regul, Lisanne, Nagarajan, Sankari, Kühnemuth, Benjamin, Johnsen, Steven A., Hebrok, Matthias, Siveke, Jens, Billadeau, Daniel D, Ellenrieder, Volker, Hessmann, Elisabeth
Argitaratua izan da Gastroenterology (2015)

Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

nork Emons, Georg, Spitzner, Melanie, Reineke, Sebastian, Möller, Janneke, Auslander, Noam, Kramer, Frank, Hu, Yue, Beissbarth, Tim, Wolff, Hendrik A., Rave-Fränk, Margret, Heßmann, Elisabeth, Gaedcke, Jochen, Ghadimi, B. Michael, Johnsen, Steven A., Ried, Thomas, Grade, Marian
Argitaratua izan da Mol Cancer Res (2017)

ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells

nork Sen, Madhobi, Wang, Xin, Hamdan, Feda H., Rapp, Jacobe, Eggert, Jessica, Kosinsky, Robyn Laura, Wegwitz, Florian, Kutschat, Ana Patricia, Younesi, Fereshteh S., Gaedcke, Jochen, Grade, Marian, Hessmann, Elisabeth, Papantonis, Argyris, Strӧbel, Philipp, Johnsen, Steven A.
Argitaratua izan da Clin Epigenetics (2019)

GSK-3β governs inflammation-induced NFATc2 signaling hubs to promote pancreatic cancer progression

nork Baumgart, Sandra, Chen, Nai-ming, Zhang, Jin-San, Billadeau, Daniel D., Gaisina, Irina, Kozikowski, Alan P., Singh, Shiv, Fink, Daniel, Ströbel, Philipp, Klindt, Caroline, Zhang, Lizhi, Bamlet, William R., Koenig, Alexander, Hessmann, Elisabeth, Gress, Thomas, Ellenrieder, Volker, Neesse, Albrecht
Argitaratua izan da Mol Cancer Ther (2016)

Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites

nork Patzak, Melanie S., Kari, Vijayalakshmi, Patil, Shilpa, Hamdan, Feda H., Goetze, Robert G., Brunner, Marius, Gaedcke, Jochen, Kitz, Julia, Jodrell, Duncan I., Richards, Frances M., Pilarsky, Christian, Gruetzmann, Robert, Rümmele, Petra, Knösel, Thomas, Hessmann, Elisabeth, Ellenrieder, Volker, Johnsen, Steven A., Neesse, Albrecht
Argitaratua izan da EBioMedicine (2019)

Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition

nork Russell, Ronan, Perkhofer, Lukas, Liebau, Stefan, Lin, Qiong, Lechel, André, Feld, Fenja M, Hessmann, Elisabeth, Gaedcke, Jochen, Güthle, Melanie, Zenke, Martin, Hartmann, Daniel, von Figura, Guido, Weissinger, Stephanie E, Rudolph, Karl-Lenhard, Möller, Peter, Lennerz, Jochen K, Seufferlein, Thomas, Wagner, Martin, Kleger, Alexander
Argitaratua izan da Nat Commun (2015)

Inflammation induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer initiation by Kras(G12D)

nork Baumgart, Sandra, Chen, Nai-ming, Siveke, Jens T., König, Alexander, Zhang, Jin-San, Singh, Shiv K., Wolf, Elmar, Bartkuhn, Marek, Esposito, Irene, Heßmann, Elisabeth, Reinecke, Johanna, Nikorowitsch, Julius, Brunner, Marius, Singh, Garima, Fernandez-Zapico, Martin E., Smyrk, Thomas, Bamlet, William R., Eilers, Martin, Neesse, Albrecht, Gress, Thomas M., Billadeau, Daniel D., Tuveson, David, Urrutia, Raul, Ellenrieder, Volker
Argitaratua 2014

Antithetical NFATc1–Sox2 and p53–miR200 signaling networks govern pancreatic cancer cell plasticity

nork Singh, Shiv K, Chen, Nai-Ming, Hessmann, Elisabeth, Siveke, Jens, Lahmann, Marlen, Singh, Garima, Voelker, Nadine, Vogt, Sophia, Esposito, Irene, Schmidt, Ansgar, Brendel, Cornelia, Stiewe, Thorsten, Gaedcke, Jochen, Mernberger, Marco, Crawford, Howard C, Bamlet, William R, Zhang, Jin-San, Li, Xiao-Kun, Smyrk, Thomas C, Billadeau, Daniel D, Hebrok, Matthias, Neesse, Albrecht, Koenig, Alexander, Ellenrieder, Volker
Argitaratua izan da EMBO J (2015)

Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer

nork Gout, Johann, Perkhofer, Lukas, Morawe, Mareen, Arnold, Frank, Ihle, Michaela, Biber, Stephanie, Lange, Sebastian, Roger, Elodie, Kraus, Johann M, Stifter, Katja, Hahn, Stephan A, Zamperone, Andrea, Engleitner, Thomas, Müller, Martin, Walter, Karolin, Rodriguez-Aznar, Eva, Sainz Jr, Bruno, Hermann, Patrick C, Hessmann, Elisabeth, Müller, Sebastian, Azoitei, Ninel, Lechel, André, Liebau, Stefan, Wagner, Martin, Simeone, Diane M, Kestler, Hans A, Seufferlein, Thomas, Wiesmüller, Lisa, Rad, Roland, Frappart, Pierre-Olivier, Kleger, Alexander
Argitaratua izan da Gut (2021)