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Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Activation of Wnt/β-catenin signaling plays a central role in the development and progression of colorectal cancer (CRC). The Wnt-transcription factor, TCF7L2, is overexpressed in primary rectal cancers that are resistant to chemoradiotherapy (CRT) and TCF7L2 mediates resistance to CRT. However, it...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Emons, Georg, Spitzner, Melanie, Reineke, Sebastian, Möller, Janneke, Auslander, Noam, Kramer, Frank, Hu, Yue, Beissbarth, Tim, Wolff, Hendrik A., Rave-Fränk, Margret, Heßmann, Elisabeth, Gaedcke, Jochen, Ghadimi, B. Michael, Johnsen, Steven A., Ried, Thomas, Grade, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772978/
https://ncbi.nlm.nih.gov/pubmed/28811361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0205
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