KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy

BACKGROUND AND PURPOSE: KRAS and BRAF are mutated in 35% and 10% of colorectal cancers, respectively. However, data specifically for locally advanced rectal cancers are scarce, and the frequency of KRAS mutations in codons 61 and 146 remains to be established. MATERIALS AND METHODS: DNA was isolated...

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Publicado en:Radiother Oncol
Autores principales: Gaedcke, Jochen, Grade, Marian, Jung, Klaus, Schirmer, Markus, Jo, Peter, Obermeyer, Christoph, Wolff, Hendrik A., Herrmann, Markus K., Beissbarth, Tim, Becker, Heinz, Ried, Thomas, Ghadimi, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373270/
https://ncbi.nlm.nih.gov/pubmed/19913317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2009.10.001
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